过去40多年来,癌症持续名列国人十大疾病死因之首,根据110年癌症登记资料,新发生癌症人数为12万1762人,其中罹患皮肤癌者占3.2%(3954人),位居十大癌症第9名,不可不慎。好消息是,美国莫德纳(Moderna)和默克(Merck,亦称默沙东)药厂昨(14)日宣布研发皮肤癌疫苗取得重大进展,患者的复发几率大大降低49%。
美国哥伦比亚广播公司(CBS)报导,根据莫德纳与默克药厂所做的临床实验,在157名患有黑色素瘤第三/四期、并切除肿瘤的随机患者中,一半的病患每3周接种1毫克mRNA皮肤癌疫苗(mRNA-4157),一共接种9次,同时每3周注射200毫克抗癌药物“吉舒达”(Keytruda),时间长达一年;另一组病患则只接受吉舒达注射。
实验结果显示,与单独接受抗癌药物“吉舒达”的患者相比,同时接种mRNA皮肤癌疫苗的病患,3年后癌症复发或死亡的几率降低了49%。接下来药厂将着手完成第3期临床实验,期待早日带给病患更多治疗选择。
根据公开资料,黑色素瘤亦称恶性黑色素癌,在所有皮肤癌中死亡率最高,患病年龄层从婴儿到老年人都有可能。白种人好发于日晒部位,黄种人则以四肢末端居多,特别好发于手掌和脚掌部位。
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